SCHEMBL7525072

SCHEMBL7525072

CC(=O)OC(CON(C(C)=O)C(=O)NC1CCCCC1)CN1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 2/20 0.38
MAPK1 P28482 2/20 0.36
ALDH1A1 P00352 1/20 0.36
SLC18A3 Q16572 1/20 0.35
TSHR P16473 1/20 0.35
DRD4 P21917 1/20 0.35
SLC6A2 P23975 1/20 0.35
CCKAR P32238 1/20 0.35
OPRM1 P35372 1/20 0.35
DRD3 P35462 1/20 0.35
SCN1A P35498 1/20 0.35
OPRK1 P41145 1/20 0.35
HTR2B P41595 1/20 0.35
SLC6A3 Q01959 1/20 0.35
KCNH2 Q12809 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3066709 0.79 ALDH1A1 (0.45) ABCB1MAPK1ALDH1A1CYP3A4L3MBTL1
Hydrochloric Acid SCHEMBL7484668 0.78 ALDH1A1 (0.44) ABCB1MAPK1ALDH1A1SLC18A3L3MBTL1
Hydrochloric Acid SCHEMBL8791052 0.68 ABCB1 (0.44) ABCB1ALDH1A1SLC18A3DRD4SLC6A2
SCHEMBL5214576 0.68 ABCB1 (0.44) ABCB1ALDH1A1SLC18A3TSHRDRD4
SCHEMBL10555746 0.68 SLC18A3 (0.56) ABCB1ALDH1A1SLC18A3TSHRDRD4
SCHEMBL5144884 0.68 ABCB1 (0.44) ABCB1ALDH1A1SLC18A3TSHRDRD4
SCHEMBL5144567 0.66 SLC18A3 (0.43) ABCB1ALDH1A1SLC18A3TSHRDRD4
SCHEMBL5144569 0.66 MAPT (0.44) ABCB1ALDH1A1SLC18A3DRD4SLC6A2
SCHEMBL10553065 0.65 SLC18A3 (0.44) ABCB1ALDH1A1SLC18A3TSHRDRD4
SCHEMBL10885369 0.65 EPHX1 (0.47) ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0832079-B1 ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS BIOREX KUTATO FEJLESZTOE KFT (HU) 2002-03-27 EP disclosed
US-6002002-A Anti-ischaemic hydroxylamine derivatives and pharmaceutical compositions BIOREX RESEARCH & DEVELOPMENT CO. (HU) 1999-12-14 US disclosed
EP-0832079-A1 ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS BIOREX KUTATO ES FEJLESZTÖ RT. (HU) 1998-04-01 EP disclosed
WO-1997000251-A1 ANTI-ISCHAEMIC HYDROXYLAMINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS BIOREX KUTATO ES FEJLESZTO RT. (HU) 1997-01-03 WO disclosed