Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 10/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30091228 | 0.82 | HTR6 (0.55) | HTR6L3MBTL1POLBPPARGFABP4 | |
| SCHEMBL2649774 | 0.82 | HTR6 (0.55) | HTR6L3MBTL1POLBPPARGFABP4 | |
| SCHEMBL1894102 | 0.81 | HTR6 (0.61) | HTR6L3MBTL1POLBPPARGFABP4 | |
| SCHEMBL13575035 | 0.76 | HTR6 (0.56) | HTR6L3MBTL1POLBPPARGFABP4 | |
| SCHEMBL3226178 | 0.76 | HTR6 (0.56) | HTR6L3MBTL1POLBPPARGFABP4 | |
| SCHEMBL29523550 | 0.76 | L3MBTL1 (0.60) | HTR6L3MBTL1POLBPPARGFABP4 | |
| SCHEMBL482811 | 0.76 | HTR6 (0.60) | HTR6L3MBTL1POLBPPARGFABP4 | |
| SCHEMBL17049298 | 0.76 | HTR6 (0.56) | HTR6L3MBTL1POLBPPARGFABP4 | |
| SCHEMBL4446722 | 0.76 | HTR6 (0.59) | HTR6L3MBTL1POLBPPARGRAPGEF4 | |
| SCHEMBL1513414 | 0.76 | L3MBTL1 (0.60) | HTR6L3MBTL1POLBPPARGFABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105761-A | Preparation method of 3, 3-disubstituted-1-indenone compound | 湖南师范大学 | 2023-11-24 | — | — | CN | disclosed |