Sugi Predict

Sugi Predict / Compounds / SCHEMBL1513414

SCHEMBL1513414

SCHEMBL1513414

Cc1ccc(S(=O)(=O)n2ccc3cc(Br)ccc32)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.60
▸ HTT P42858 3/20 0.60
▸ MEN1 O00255 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ PKM P14618 1/20 0.60
▸ HTR6 P50406 10/20 0.56
▸ FABP4 P15090 3/20 0.52
▸ POLB P06746 1/20 0.50
▸ FABP3 P05413 1/20 0.50
▸ FABP2 P12104 1/20 0.50
▸ FABP5 Q01469 1/20 0.50
▸ PPARG P37231 1/20 0.48
▸ HDAC1 Q13547 1/20 0.48
▸ HDAC6 Q9UBN7 1/20 0.48
▸ RAPGEF4 Q8WZA2 2/20 0.47
▸ MAPT P10636 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.47
▸ ALDH1A1 P00352 1/20 0.46
▸ LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29523550 1.00 L3MBTL1 (0.60) L3MBTL1HTTMEN1KMT2APKM
SCHEMBL29408218 0.88 MEN1 (0.60) L3MBTL1HTTMEN1KMT2APKM
SCHEMBL2573218 0.88 MEN1 (0.60) L3MBTL1HTTMEN1KMT2APKM
SCHEMBL1894102 0.88 HTR6 (0.61) L3MBTL1HTTMEN1KMT2APKM
SCHEMBL34460046 0.85 HTR6 (0.68) L3MBTL1HTTMEN1KMT2APKM
SCHEMBL3526978 0.85 HTR6 (0.68) L3MBTL1HTTMEN1KMT2APKM
SCHEMBL948701 0.85 HTR6 (0.58) L3MBTL1HTTMEN1KMT2APKM
SCHEMBL946543 0.85 HTR6 (0.67) L3MBTL1HTTMEN1KMT2APKM
SCHEMBL3226178 0.82 HTR6 (0.56) L3MBTL1HTTMEN1KMT2AHTR6
SCHEMBL482811 0.82 HTR6 (0.60) L3MBTL1HTTMEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260084134-A1 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS UNIV CORNELL (US) 2026-03-26 — — US disclosed
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US disclosed
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CFD RES CORPORATION (US) 2025-12-18 — — US disclosed
US-20240239784-A1 INDOLE COMPOUNDS AND METHODS OF USE GENZYME CORPORATION 2024-07-18 — — US disclosed
EP-4396176-A1 INDOLE COMPOUNDS AND USES THEREOF IN THE TREATEMENT OF CYSTIC FIBROSIS GENZYME CORPORATION (US) 2024-07-10 — — EP disclosed
US-RE49931-E1 [1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2024-04-23 — — US disclosed
US-RE49893-E1 [1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2024-04-02 — — US disclosed
US-RE49880-E1 [1,2,4]triazolo[1,5-a]pyridinyl substituted indole compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2024-03-26 — — US disclosed
WO-2023205455-A2 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS CORNELL UNIVERSITY (US) 2023-10-26 — — WO disclosed
US-20230255941-A1 [1,2,4]TRIAZOLO[1,5-A]PYRIDINYL SUBSTITUTED INDOLE COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY 2023-08-17 — — US disclosed
US-5635197-A BENZO(F)QUINOLIN-3-ONES; ANTICARCINOGENIC AGENTS; BONE DISORDERS ELI LILLY AND COMPANY (US) 1997-06-03 — — US disclosed
US-5629007-A USING BENZOQUINOLIN-3-ONE DERIVATIVES ELI LILLY AND COMPANY (US) 1997-05-13 — — US disclosed
US-5622961-A PROSTATE CANCER, SKIN DISORDERS, BALDNESS ELI LILLY AND COMPANY (US) 1997-04-22 — — US disclosed
US-5622962-A PROSTATE CANCER, SKIN DISORDERS, BALDNESS ELI LILLY AND COMPANY (US) 1997-04-22 — — US disclosed
CN-1138458-A Treatment and prevention of prostatic cancer LILLY CO ELI (US) 1996-12-25 — — CN disclosed
US-5578724-A INHIBITORS OF 5-ALPHA-REDUCTASE ELI LILLY AND COMPANY (US) 1996-11-26 — — US disclosed
WO-1996035422-A1 METHODS FOR INHIBITING BONE LOSS ELI LILLY AND COMPANY (US) 1996-11-14 — — WO disclosed
EP-0742010-A2 Benzoquinolin-3-ones to inhibit bone loss ELI LILLY AND COMPANY (US) 1996-11-13 — — EP disclosed
EP-0733365-A2 Use of benzoquinolin-3-ones for the treatment and prevention of prostatic cancer ELI LILLY AND COMPANY (US) 1996-09-25 — — EP disclosed
US-5550134-A ADMINISTERING TO A MAMMAL FROM A SERIES OF BENZOQUINOLIN-3-ONE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239784-A1 INDOLE COMPOUNDS AND METHODS OF USE CFTR, INMT, IDO1 L3MBTL1 3265/4885HTT 553/4885MEN1 2690/4885
US-20260084134-A1 STORAGE AND DELIVERY OF GASEOUS CHEMICAL REACTANTS IN CHEMICAL PROCESSES USING METAL-ORGANIC FRAMEWORKS ME3, ME2, SLC25A11 L3MBTL1 1150/4885HTT 4353/4885MEN1 452/4885
US-20250382269-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 L3MBTL1 1636/4885HTT 3039/4885MEN1 2402/4885
US-20250382268-A1 METHODS AND COMPOSITIONS FOR SELECTIVELY INHIBITING PATHOGENIC MICROBES CD14, MIF, NOD2 L3MBTL1 1636/4885HTT 3039/4885MEN1 2402/4885
US-20230255941-A1 [1,2,4]TRIAZOLO[1,5-A]PYRIDINYL SUBSTITUTED INDOLE COMPOUNDS TLR7, TLR1, TLR5 L3MBTL1 4400/4885HTT 3874/4885MEN1 1756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.