Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10319562 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MAPTMAPK1PDGFRBFGFR1 | |
| SCHEMBL29164219 | 0.89 | PDGFRB (0.44) | ALDH1A1MAPTMAPK1PDGFRBFGFR1 | |
| SCHEMBL4993186 | 0.82 | PDGFRB (0.42) | ALDH1A1MAPTMAPK1PDGFRBFGFR1 | |
| SCHEMBL29164229 | 0.80 | PDGFRB (0.43) | ALDH1A1MAPTMAPK1PDGFRBFGFR1 | |
| SCHEMBL2699920 | 0.79 | PDGFRB (0.45) | ALDH1A1MAPTMAPK1PDGFRBFGFR1 | |
| SCHEMBL27883380 | 0.78 | SIRT6 (0.48) | ALDH1A1MAPTPDGFRBFGFR1PDGFRA | |
| SCHEMBL8057515 | 0.78 | MAPT (0.40) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL21955292 | 0.78 | CA1 (0.38) | ALDH1A1MAPTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12035936 | 0.78 | POLB (0.39) | ALDH1A1MAPTKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL2698796 | 0.77 | LMNA (0.44) | ALDH1A1MAPTMAPK1PDGFRBFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105916-B | Benzofuran compound and medical application thereof | 希格生科（深圳）有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-117105916-A | Benzofuran compound and medical application thereof | 希格生科（深圳）有限公司 | 2023-11-24 | — | — | CN | disclosed |