Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.55 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568800 | 1.00 | CA12 (0.55) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL10662835 | 0.84 | CA12 (0.53) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL6581393 | 0.82 | CA12 (0.52) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL30321500 | 0.80 | CA12 (0.50) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL6195893 | 0.79 | RAB9A (0.56) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL30804587 | 0.79 | RAB9A (0.56) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL9112778 | 0.79 | CA12 (0.49) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL7957507 | 0.78 | CA12 (0.47) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL5722231 | 0.78 | ADORA3 (0.48) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL29018547 | 0.77 | CA12 (0.44) | CA12CA9BRD4BRPF1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157072-A | Novel cyclopento [ c ] pyrrole NR2B negative allosteric modulators | 诺华股份有限公司 | 2023-12-01 | — | — | CN | disclosed |