Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10662835 | 0.86 | CA12 (0.53) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL6195893 | 0.85 | RAB9A (0.56) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL30804587 | 0.85 | RAB9A (0.56) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL30672091 | 0.82 | CA12 (0.55) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL6568800 | 0.82 | CA12 (0.55) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL28320396 | 0.79 | KCNMA1 (0.44) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL30321500 | 0.78 | CA12 (0.50) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL27637776 | 0.78 | CA12 (0.42) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL27916356 | 0.78 | CA12 (0.42) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL27485103 | 0.76 | KMO (0.41) | MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107056810-B | A kind of preparation method of Carbostyril carboxylic acid derivatives | 广东省中医院 | 2019-04-26 | — | — | CN | claimed |
| CN-107056810-A | A kind of preparation method of Carbostyril carboxylic acid derivatives | 广东省中医院 | 2017-08-18 | — | — | CN | claimed |
| CN-106687179-A | Methods for treating infections | 梅琳塔治疗公司 | 2017-05-17 | — | — | CN | claimed |
| CN-106572982-A | Antimicrobial compositions with effervescent agents | 梅琳塔治疗公司 | 2017-04-19 | — | — | CN | claimed |
| CN-106237335-A | A kind of dermatological field antibacterial | 陈广圣 | 2016-12-21 | — | — | CN | claimed |
| CN-102215690-A | Antimicrobial compositions | RIB X PHARMACEUTICALS INC | 2011-10-12 | — | — | CN | claimed |
| CN-101817820-B | Method for synthesizing moxifloxacin hydrochloride | CHONGQING BOTENG FINE CHEMICAL CO LTD | 2011-10-05 | — | — | CN | claimed |
| CN-101817820-A | Method for synthesizing moxifloxacin hydrochloride | CHONGQING BOTENG FINE CHEMICAL CO LTD | 2010-09-01 | — | — | CN | claimed |
| CN-100410249-C | 7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) Q uinolonecarboxylic acid derivative | KYORIN SEIYAKU KK (JP) | 2008-08-13 | — | — | CN | claimed |
| CN-100395244-C | Quinolone carboxylic acid derivatives or their salts | TOYAMA CHEMICAL CO LTD (JP) | 2008-06-18 | — | — | CN | claimed |
| CN-1035945-C | 5-Alkylquinolonecarboxylic acids | BAYER AG (DE) | 1997-09-24 | — | — | CN | claimed |
| CN-1128995-A | Novel Quinolone carboxylic acid derivative | DONG WHA PHARM IND CO LTD (KR) | 1996-08-14 | — | — | CN | claimed |
| CN-1111629-A | 5-vinyl-, 5-ethynylquinolone-and 5-vinyl-, 5-ethynylnaphthyridonecarboxylic acids | BAYER AG (DE) | 1995-11-15 | — | — | CN | claimed |
| CN-1108968-A | Use of ion exchange resins loaded with quioolonecarboxylic acid derivatives | BAYER AG (DE) | 1995-09-27 | — | — | CN | claimed |
| CN-1094405-A | New Carbostyril carboxylic acid derivatives and preparation method thereof | KOREA RES INST CHEM TECH (KR) | 1994-11-02 | — | — | CN | claimed |
| CN-1046162-A | The 5-Alkylquinolonecarboxacids acids | BAYER AG (DE) | 1990-10-17 | — | — | CN | claimed |
| CN-1037335-A | The preparation method of 1-cyclopropyl Quinolone carboxylic acid and derivative thereof | BAYER AG (DE) | 1989-11-22 | — | — | CN | claimed |
| CN-1037147-A | N-cyclopropyl aniline and the application in preparation 1-cyclopropyl quinolone carboxylic acid and its derivative thereof | BAYER AG (DE) | 1989-11-15 | — | — | CN | claimed |
| CN-88103473-A | Preparation and application of ion exchange resin loaded with quinolone carboxylic acid derivative | — | 1988-12-28 | — | — | CN | claimed |
| CN-86104256-A | 1, the preparation method of 8-bridging 4-quinolone-3-carboxylic-acid | — | 1987-03-18 | — | — | CN | claimed |