Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16391071 | 1.00 | ATAD2 (0.42) | ATAD2ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL25804417 | 0.91 | KMT2A (0.44) | ATAD2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL18426670 | 0.85 | ATAD2 (0.43) | ATAD2ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL3656320 | 0.83 | MAPT (0.49) | ATAD2ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL23529776 | 0.82 | CYP1A2 (0.43) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL29804017 | 0.82 | CYP1A2 (0.43) | ALDH1A1MEN1KMT2AUSP2CDK4 | |
| SCHEMBL6290425 | 0.81 | KDM4E (0.39) | ATAD2ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL6285804 | 0.80 | KDM4E (0.38) | ATAD2ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL7120843 | 0.80 | KDM4E (0.38) | ATAD2ALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL6287165 | 0.80 | ALDH1A1 (0.44) | ATAD2ALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486865-A | Pyrimidine derivatives as kinase inhibitors | 艾森医药公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-112592334-B | Pyrimidine derivatives as kinase inhibitors | 艾森医药公司 | 2023-10-27 | — | — | CN | disclosed |