Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | ESRRG | P62508 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285804 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL6290425 | 0.99 | KDM4E (0.39) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL18426670 | 0.83 | ATAD2 (0.43) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL16391071 | 0.80 | ATAD2 (0.42) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL30672811 | 0.80 | ATAD2 (0.42) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL25753067 | 0.80 | ALDH1A1 (0.62) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL17525535 | 0.76 | NOS3 (0.36) | KDM4EALDH1A1MEN1KMT2AAPP | |
| SCHEMBL6290940 | 0.76 | RARB (0.38) | KDM4EALDH1A1MEN1KMT2AAPP | |
| SCHEMBL6287376 | 0.76 | KDM4E (0.35) | KDM4EALDH1A1HTR1AHTT | |
| SCHEMBL3656320 | 0.75 | MAPT (0.49) | KDM4EALDH1A1MEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | claimed |
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | L'OREAL S.A. (FR) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028977-A1 | Oxidation dyeing composition for keratinous fibres and dyeing method using same | KRT18, NDUFB5, NDUFB4 | KDM4E 1488/4885ALDH1A1 139/4885MEN1 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.