Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 6/20 | 0.41 |
| ▸ | CCND1 | P24385 | 6/20 | 0.41 |
| ▸ | HTR2A | P28223 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370787 | 1.00 | PRKCI (0.55) | PRKCIEGFRPLAUPLGBRPF1 | |
| SCHEMBL6789563 | 0.87 | PRKCI (0.56) | PRKCIEGFRPLAUPLGBRPF1 | |
| SCHEMBL3650822 | 0.82 | PRKCI (0.59) | PRKCIEGFRPLAUPLGBRPF1 | |
| SCHEMBL13836419 | 0.82 | PRKCI (0.55) | PRKCIEGFRPLAUPLGBRPF1 | |
| SCHEMBL16219087 | 0.81 | PLG (0.43) | PLAUPLGCDK4CCND1HTR2A | |
| SCHEMBL5089820 | 0.79 | PRKCI (0.56) | PRKCIEGFRPLAUPLGBRPF1 | |
| SCHEMBL216229 | 0.78 | HTR2C (0.61) | PRKCIEGFRBRPF1NTSR1HTR2A | |
| SCHEMBL3653449 | 0.78 | PRKCI (0.54) | PRKCIEGFRPLAUPLGBRPF1 | |
| SCHEMBL30411128 | 0.78 | HTR2C (0.61) | PRKCIEGFRBRPF1NTSR1HTR2A | |
| SCHEMBL31265088 | 0.78 | PRKCI (0.58) | PRKCIEGFRPLAUBRPF1NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486865-A | Pyrimidine derivatives as kinase inhibitors | 艾森医药公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-112592334-B | Pyrimidine derivatives as kinase inhibitors | 艾森医药公司 | 2023-10-27 | — | — | CN | disclosed |