Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.51 |
| ▸ | STS | P08842 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1558412 | 1.00 | NAMPT (0.54) | NAMPTKDM4EMAPTTHRBGPR119 | |
| SCHEMBL22608979 | 0.92 | PDE4B (0.58) | KDM4EMAPTTHRBGPR119DRD2 | |
| SCHEMBL30563607 | 0.87 | GPR119 (0.65) | NAMPTKDM4EMAPTTHRBGPR119 | |
| SCHEMBL23258567 | 0.86 | MAPT (0.53) | NAMPTKDM4EMAPTTHRBGPR119 | |
| SCHEMBL4031537 | 0.86 | SIGMAR1 (0.54) | DRD2PDE4BDRD3 | |
| SCHEMBL30376009 | 0.86 | GPR119 (0.54) | NAMPTKDM4EMAPTTHRBGPR119 | |
| SCHEMBL21523778 | 0.86 | TP53 (0.56) | NAMPTKDM4EMAPTTHRBGPR119 | |
| SCHEMBL30014833 | 0.86 | NAMPT (0.53) | NAMPTKDM4EMAPTTHRBGPR119 | |
| SCHEMBL1427529 | 0.86 | NAMPT (0.53) | NAMPTKDM4EMAPTTHRBGPR119 | |
| SCHEMBL15043876 | 0.86 | NAMPT (0.53) | NAMPTKDM4EMAPTTHRBGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4650353-A1 | 4-ALKOXY BENZIMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVE SERVING AS GLP-1 RECEPTOR AGONIST | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2025-11-19 | — | — | EP | disclosed |
| EP-4536224-A1 | INDAZOLE CONTAINING MACROCYCLES AND THEIR USE | Blossomhill Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2024149080-A1 | 4-ALKOXY BENZIMIDAZOLE-6-CARBOXYLIC ACID DERIVATIVE SERVING AS GLP-1 RECEPTOR AGONIST | 中国科学院上海药物研究所 | 2024-07-18 | — | — | WO | disclosed |