SCHEMBL30673294

SCHEMBL30673294

COc1cc(Br)cc[n+]1[O-]

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15024923 1.00 HDAC8 (0.34) HDAC8
SCHEMBL5944757 0.77 BCL2 (0.41)
SCHEMBL15024769 0.75 ALDH1A1 (0.38)
SCHEMBL1475835 0.71
SCHEMBL12938268 0.70 HDAC8 (0.36) HDAC8
SCHEMBL27882709 0.70
SCHEMBL10330647 0.68 IDH1 (0.37) HDAC8
SCHEMBL27077478 0.67 ACHE (0.41)
SCHEMBL25283800 0.67
SCHEMBL30471742 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119698416-A Imidazo (1, 2-A) pyridine derivatives as RIPK2 inhibitors 英特莱治疗公司 2025-03-25 CN disclosed
EP-4518974-A1 IMIDAZO(1,2-A)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS Interline Therapeutics, Inc. (US) 2025-03-12 EP disclosed
WO-2023239941-A1 IMIDAZO(1,2-A)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS INTERLINE THERAPEUTICS INC. (US) 2023-12-14 WO disclosed