Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TAF1 | P21675 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420318 | 0.89 | AHR (0.50) | KEAP1PDPK1BACE1AHRMCL1 | |
| SCHEMBL29361477 | 0.89 | AHR (0.50) | KEAP1PDPK1BACE1AHRMCL1 | |
| Hydrochloric Acid SCHEMBL27757229 | 0.88 | AHR (0.48) | KEAP1PDPK1BACE1AHRMCL1 | |
| Hydrochloric Acid SCHEMBL3826755 | 0.88 | AHR (0.48) | KEAP1PDPK1BACE1AHRMCL1 | |
| Hydrochloric Acid SCHEMBL29363603 | 0.88 | AHR (0.48) | KEAP1PDPK1BACE1AHRMCL1 | |
| Trifluoroacetic Acid SCHEMBL29364273 | 0.81 | KEAP1 (0.47) | KEAP1PDPK1BACE1AHRMCL1 | |
| Cadaverine Tartrate SCHEMBL28147371 | 0.81 | KEAP1 (0.47) | KEAP1PDPK1BACE1AHRMCL1 | |
| SCHEMBL97591 | 0.74 | AHR (0.50) | KEAP1PDPK1BACE1AHRCA1 | |
| Quinoline SCHEMBL27950148 | 0.74 | ALDH1A1 (0.49) | AHRCA1CA2HTT | |
| Formic Acid SCHEMBL28403706 | 0.74 | AHR (0.78) | KEAP1PDPK1BACE1AHRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2023-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348439-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | KEAP1 2275/4885PDPK1 1334/4885BACE1 2736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.