SCHEMBL30674291

SCHEMBL30674291

C[C@@H](O)[C@H](N)C(=O)NC(=O)Nc1ncnc2c1ncn2[C@]1(O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TARS1 P26639 2/20 0.37
▸ ADORA3 P0DMS8 1/20 0.37
▸ SLC29A1 Q99808 1/20 0.36
▸ ADORA1 P30542 1/20 0.36
▸ ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21274225 1.00 TARS1 (0.37) TARS1ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL30379388 0.95 ADORA3 (0.37) ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL2033389 0.90 ADORA1 (0.38) TARS1ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL30037173 0.90 ADORA1 (0.38) TARS1ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL17371759 0.88 TARS1 (0.37) TARS1SLC29A1ADORA1
SCHEMBL27641587 0.85 SLC29A1 (0.38) ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL29089525 0.83 TARS1 (0.39) TARS1SLC29A1ADORA1
SCHEMBL16987222 0.81 TARS1 (0.38) TARS1SLC29A1ADORA1
SCHEMBL28564130 0.81 TARS1 (0.38) TARS1SLC29A1ADORA1
SCHEMBL29435121 0.81 TARS1 (0.38) TARS1SLC29A1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4577243-A1 STABLE LIPID OR LIPIDOID NANOPARTICLE SUSPENSIONS Ethris GmbH (DE) 2025-07-02 — — EP disclosed
EP-4536825-A2 SYSTEMS FOR ENHANCING TARGET MRNA EXPRESSION AND USES THEREOF The Johns Hopkins University (US) 2025-04-16 — — EP disclosed
WO-2025045767-A1 STABILIZED LIPID AND LIPIDOID NANOPARTICLE FORMULATIONS WITH SPECIFIC SURFACTANT PROPERTIES FOR ENHANCED PHARMACEUTICAL APPLICATIONS ETHRIS GMBH (DE) 2025-03-06 — — WO disclosed
WO-2025038850-A1 LIPID NANOPARTICLES AND METHODS FOR SENSITIZING RESPONSE TO AN IMMUNOTHERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 — — WO disclosed
WO-2023240254-A9 SYSTEMS FOR ENHANCING TARGET MRNA EXPRESSION AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2024-12-19 — — WO disclosed
WO-2024042236-A1 STABLE LIPID OR LIPIDOID NANOPARTICLE SUSPENSIONS ETHRIS GMBH (DE) 2024-02-29 — — WO disclosed
WO-2023240254-A2 SYSTEMS FOR ENHANCING TARGET MRNA EXPRESSION AND USES THEREOF THE JOHNS HOPKINS UNIVERSITY (US) 2023-12-14 — — WO disclosed
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