SCHEMBL21274225

SCHEMBL21274225

CC(O)C(N)C(=O)NC(=O)Nc1ncnc2c1ncn2[C@]1(O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TARS1 P26639 2/20 0.37
▸ ADORA3 P0DMS8 1/20 0.37
▸ SLC29A1 Q99808 1/20 0.36
▸ ADORA1 P30542 1/20 0.36
▸ ADORA2A P29274 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30674291 1.00 TARS1 (0.37) TARS1ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL30379388 0.95 ADORA3 (0.37) ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL2033389 0.90 ADORA1 (0.38) TARS1ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL30037173 0.90 ADORA1 (0.38) TARS1ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL17371759 0.88 TARS1 (0.37) TARS1SLC29A1ADORA1
SCHEMBL27641587 0.85 SLC29A1 (0.38) ADORA3SLC29A1ADORA1ADORA2A
SCHEMBL29089525 0.83 TARS1 (0.39) TARS1SLC29A1ADORA1
SCHEMBL16987222 0.81 TARS1 (0.38) TARS1SLC29A1ADORA1
SCHEMBL28564130 0.81 TARS1 (0.38) TARS1SLC29A1ADORA1
SCHEMBL29435121 0.81 TARS1 (0.38) TARS1SLC29A1ADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4379052-A2 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION Ethris GmbH (DE) 2024-06-05 — — EP claimed
US-12612658-B2 RNA replication using transcription polymerases THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-04-28 — — US disclosed
US-20260071215-A1 SYSTEMS FOR ENHANCING TARGET MRNA EXPRESSION AND USES THEREOF UNIV JOHNS HOPKINS (US) 2026-03-12 — — US disclosed
EP-3752610-B1 POLYRIBONUCLEOTIDE CONTAINING DEUTERATED NUCLEOTIDES ETHRIS GMBH (DE) 2026-01-28 — — EP disclosed
US-12522821-B2 Polyribonucleotide containing deuterated nucleotides ETHRIS GMBH (DE) 2026-01-13 — — US disclosed
US-12509679-B2 mRNA purification by tangential flow filtration ETHRIS GMBH (DE) 2025-12-30 — — US disclosed
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS TRILINK BIOTECHNOLOGIES, LLC 2025-06-26 — — US disclosed
EP-4553084-A2 USE OF IFN-LAMBDA MRNA FOR TREATING VIRAL INFECTIONS Ethris GmbH (DE) 2025-05-14 — — EP disclosed
EP-4499824-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2025-02-05 — — EP disclosed
EP-4240396-B1 IFN-LAMBDA MRNA FOR TREATING VIRAL INFECTIONS ETHRIS GMBH (DE) 2025-01-01 — — EP disclosed
EP-3924487-A1 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION ethris GmbH (DE) 2021-12-22 — — EP disclosed
US-20210317179-A1 PRECISELY ENGINEERED STEALTHY MESSENGER RNAS AND OTHER POLYNUCLEOTIDES KERNAL BIOLOGICS, INC. 2021-10-14 — — US disclosed
EP-3833360-A1 PRECISELY ENGINEERED STEALTHY MESSENGER RNAS AND OTHER POLYNUCLEOTIDES Kernal Biologics, Inc. (US) 2021-06-16 — — EP disclosed
WO-2021007233-A1 RNA REPLICATION USING TRANSCRIPTION POLYMERASES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2021-01-14 — — WO disclosed
US-20210009995-A1 POLYRIBONUCLEOTIDE CONTAINING DEUTERATED NUCLEOTIDES ETHRIS GMBH (DE) 2021-01-14 — — US disclosed
EP-3752610-A1 POLYRIBONUCLEOTIDE CONTAINING DEUTERATED NUCLEOTIDES ethris GmbH (DE) 2020-12-23 — — EP disclosed
WO-2020165158-A1 MRNA PURIFICATION BY TANGENTIAL FLOW FILTRATION ETHRIS GMBH (DE) 2020-08-20 — — WO disclosed
WO-2020165352-A1 TREATMENT OF CILIOPATHIES ETHRIS GMBH (DE) 2020-08-20 — — WO disclosed
WO-2020033720-A1 PRECISELY ENGINEERED STEALTHY MESSENGER RNAS AND OTHER POLYNUCLEOTIDES KERNAL BIOLOGICS, INC. (US) 2020-02-13 — — WO disclosed
WO-2019158583-A1 POLYRIBONUCLEOTIDE CONTAINING DEUTERATED NUCLEOTIDES ETHRIS GMBH (DE) 2019-08-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509679-B2 mRNA purification by tangential flow filtration ELL, RNGTT, FIP1L1 TARS1 2357/4885ADORA3 2581/4885SLC29A1 1244/4885
US-20260071215-A1 SYSTEMS FOR ENHANCING TARGET MRNA EXPRESSION AND USES THEREOF UPF1, RBM26, RPRD2 TARS1 435/4885ADORA3 2047/4885SLC29A1 389/4885
US-12612658-B2 RNA replication using transcription polymerases RNGTT, POLRMT, POLM TARS1 755/4885ADORA3 238/4885SLC29A1 2504/4885
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS RNGTT, POLRMT, POLN TARS1 751/4885ADORA3 1331/4885SLC29A1 358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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