Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26930421 | 1.00 | L3MBTL1 (0.53) | L3MBTL1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8241397 | 0.92 | HTR6 (0.48) | L3MBTL1LMNAMAPTCA2CA1 | |
| SCHEMBL25238794 | 0.84 | CA1 (0.50) | L3MBTL1ALDH1A1HTTPOLBALDH3A1 | |
| SCHEMBL20437149 | 0.83 | L3MBTL1 (0.48) | L3MBTL1HTTPOLBALDH3A1NOD1 | |
| SCHEMBL26930315 | 0.81 | L3MBTL1 (0.46) | L3MBTL1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30674367 | 0.81 | L3MBTL1 (0.46) | L3MBTL1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8944259 | 0.80 | L3MBTL1 (0.67) | L3MBTL1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20210703 | 0.79 | L3MBTL1 (0.53) | L3MBTL1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30674333 | 0.79 | L3MBTL1 (0.46) | L3MBTL1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26930313 | 0.79 | L3MBTL1 (0.46) | L3MBTL1LMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536657-A1 | LATS INHIBITORS AND USES THEREOF | The USA, as represented by The Secretary, Department of Health and Human Services (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023239727-A1 | LATS INHIBITORS AND USES THEREOF | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-12-14 | — | — | WO | disclosed |