Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223298 | 1.00 | DRD2 (0.58) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL1171694 | 0.94 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL15922784 | 0.93 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL4743318 | 0.93 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL1772856 | 0.93 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL3160942 | 0.90 | DRD2 (0.56) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL9020787 | 0.88 | ALDH1A1 (0.56) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL3814692 | 0.88 | DRD2 (0.51) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL11674802 | 0.88 | DRD2 (0.66) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL10798638 | 0.86 | DRD2 (0.64) | DRD2DRD4DRD3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117105872-A | Benzodiazepine compound and preparation method and application thereof | 徐州医科大学 | 2023-11-24 | — | — | CN | claimed |
| CN-117105872-B | Benzodiazepine compound and preparation method and application thereof | 徐州医科大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-117105872-A | Benzodiazepine compound and preparation method and application thereof | 徐州医科大学 | 2023-11-24 | — | — | CN | disclosed |