Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL223298 | 0.88 | DRD2 (0.58) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL30674602 | 0.88 | DRD2 (0.58) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL1171694 | 0.83 | DRD2 (0.57) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL4743318 | 0.81 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL15922784 | 0.81 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL1772856 | 0.81 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL9020787 | 0.81 | ALDH1A1 (0.56) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL13645864 | 0.80 | DRD2 (0.50) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL3160942 | 0.79 | DRD2 (0.56) | DRD2DRD4DRD3L3MBTL1KDM4E | |
| SCHEMBL10511421 | 0.78 | ACHE (0.60) | DRD2DRD4DRD3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730148-A4 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | ABBOTT LAB (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1730148-A2 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | Abbott Laboratories (US) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005074603-A2 | AMINOBENZOXAZOLES AS THERAPEUTIC AGENTS | ABBOTT LABORATORIES (US) | 2005-08-18 | — | — | WO | disclosed |