Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21060155 | 1.00 | KDM4E (0.41) | KDM4ESTAT3HIF1ANPSR1ALDH1A1 | |
| SCHEMBL20552180 | 0.84 | MMP2 (0.40) | KDM4ESTAT3HIF1ANPSR1ALDH1A1 | |
| SCHEMBL21060383 | 0.83 | KMO (0.44) | KDM4EALDH1A1LMNAPIK3C3HPGD | |
| SCHEMBL24005756 | 0.78 | CDK8 (0.47) | KDM4ESTAT3HIF1ANPSR1ALDH1A1 | |
| SCHEMBL5925834 | 0.75 | NPSR1 (0.42) | KDM4ESTAT3HIF1ANPSR1ALDH1A1 | |
| SCHEMBL2671386 | 0.74 | PIK3C3 (0.47) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL29550479 | 0.73 | MAPK1 (0.41) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL756526 | 0.73 | MAPK1 (0.41) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL8905796 | 0.73 | TDP1 (0.47) | KDM4ESTAT3NPSR1ALDH1A1HTT | |
| SCHEMBL8832261 | 0.72 | KDM4E (0.54) | KDM4ENPSR1ALDH1A1HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | disclosed |