SCHEMBL30675403

SCHEMBL30675403

O=C(Cl)c1ccccc1S(=O)(=O)Cc1ccccc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.75
SMN1; SMN2 Q16637 1/20 0.75
HSD17B10 Q99714 1/20 0.47
CA9 Q16790 7/20 0.45
CA1 P00915 7/20 0.45
CA2 P00918 7/20 0.45
CA12 O43570 5/20 0.45
CA5A P35218 5/20 0.45
CA4 P22748 4/20 0.45
CA6 P23280 4/20 0.45
CA7 P43166 4/20 0.45
CA13 Q8N1Q1 4/20 0.45
CA14 Q9ULX7 4/20 0.45
CA5B Q9Y2D0 4/20 0.45
CA3 P07451 3/20 0.45
LMNA P02545 1/20 0.43
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 1/20 0.42
POLB P06746 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312941 0.86 TSHR (1.00) TSHRSMN1; SMN2HSD17B10CA9CA1
SCHEMBL11759546 0.83 TSHR (0.71) TSHRSMN1; SMN2HSD17B10CA9CA1
SCHEMBL11336480 0.83 TSHR (0.75) TSHRSMN1; SMN2HSD17B10CA9CA1
SCHEMBL8608902 0.80 TSHR (0.47) TSHRSMN1; SMN2CA9CA1CA2
SCHEMBL4796461 0.80 TSHR (0.71) TSHRSMN1; SMN2HSD17B10CA9CA1
SCHEMBL8750884 0.77 TSHR (0.45) TSHRSMN1; SMN2CA9CA1CA2
SCHEMBL9618785 0.76 TSHR (0.73) TSHRSMN1; SMN2HSD17B10CA9CA1
SCHEMBL8966630 0.75 ALDH1A1 (0.50) TSHRSMN1; SMN2CA9CA1CA2
SCHEMBL27643364 0.75 ALDH1A1 (0.44) TSHRSMN1; SMN2HSD17B10CA9CA1
SCHEMBL3645882 0.74 ALDH1A1 (0.48) TSHRSMN1; SMN2HSD17B10CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116802499-A Method for measuring dystrophin in tissue samples 辉瑞大药厂 2023-09-22 CN disclosed