SCHEMBL3645882

SCHEMBL3645882

O=C(Cl)c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
ALOX15 P16050 2/20 0.48
CA9 Q16790 4/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
MMP1 P03956 2/20 0.41
MMP2 P08253 2/20 0.41
MMP9 P14780 2/20 0.41
MMP8 P22894 2/20 0.41
MMP13 P45452 2/20 0.41
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CA5A P35218 1/20 0.39
TSHR P16473 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
F2 P00734 2/20 0.38
PRSS1 P07477 2/20 0.38
PRSS2 P07478 2/20 0.38
PRSS3 P35030 2/20 0.38
BCAT2 O15382 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7917646 0.84 CA1 (0.42) ALDH1A1ALOX15CA9CA1CA2
SCHEMBL8966630 0.84 ALDH1A1 (0.50) ALDH1A1ALOX15CA9CA1CA2
SCHEMBL8747678 0.83 ALDH1A1 (0.48) ALDH1A1ALOX15CA9CA1CA2
SCHEMBL135801 0.83 CA1 (0.60) ALDH1A1ALOX15CA9CA1CA2
SCHEMBL27799698 0.82 ALDH1A1 (0.39) ALDH1A1ALOX15CA9CA1CA2
SCHEMBL628149 0.82 ALDH1A1 (0.42) ALDH1A1ALOX15CA9CA1CA2
SCHEMBL533002 0.81 BCAT2 (0.43) ALDH1A1ALOX15CA9CA1CA2
Hydrochloric Acid SCHEMBL3893485 0.81 CA1 (0.58) ALDH1A1ALOX15CA9CA1CA2
SCHEMBL30527132 0.81 CA1 (0.67) ALDH1A1ALOX15CA9CA1CA2
SCHEMBL5860671 0.81 ALDH1A1 (0.52) ALDH1A1ALOX15CA9CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112876875-B Disazo reactive yellow dye and preparation method and application thereof 湖北丽源科技股份有限公司 2022-05-20 CN claimed
CN-112876875-A Disazo reactive yellow dye and preparation method and application thereof 湖北丽源科技股份有限公司 2021-06-01 CN claimed
EP-2636675-B1 DIPHOSPHONATE COMPOUNDS AND PREPARATION METHOD AND USE THEREOF CHENGDU YUNKE PHARMACEUTICAL CO LTD (CN) 2016-05-18 EP claimed
CN-100558704-C The dichloro monomer and the synthetic method thereof of the sulfone ketone containing structure of poly (aryl ether sulfone ketone) DALIAN LIGHT IND COLLEGE (CN) 2009-11-11 CN claimed
US-4645528-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1987-02-24 US claimed
EP-0203220-A1 Benzolactamsultams BAYER AG (DE) 1986-12-03 EP claimed
EP-0154811-A2 Coupling agents between mineral fillers and polymers Plüss-Staufer AG (CH) 1985-09-18 EP claimed
WO-1985003505-A2 COUPLING AGENT BETWEEN MINERAL FILLERS AND POLYMERS PLÜSS-STAUFER AG (CH) 1985-08-15 WO claimed
US-4211723-A PHOSGENE, SULFOBENZOIC ACID, DIMETHYLFORMAMIDE IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1980-07-08 US claimed
US-4057555-A FROM PHOSGENE AND O-SULFOBENZOIC ACID, DIMETHYLFORMAMIDE, ALCOHOL, AMMONIA IHARA CHEMICAL INDUSTRY CO., LTD. (JA) 1977-11-08 US claimed
JP-52062241-A None JP disclosed
CN-112876875-B Disazo reactive yellow dye and preparation method and application thereof 湖北丽源科技股份有限公司 2022-05-20 CN disclosed
CN-112876875-B Disazo reactive yellow dye and preparation method and application thereof 湖北丽源科技股份有限公司 2022-05-20 CN disclosed
CN-112876875-A Disazo reactive yellow dye and preparation method and application thereof 湖北丽源科技股份有限公司 2021-06-01 CN disclosed
CN-112876875-A Disazo reactive yellow dye and preparation method and application thereof 湖北丽源科技股份有限公司 2021-06-01 CN disclosed
US-4211723-A PHOSGENE, SULFOBENZOIC ACID, DIMETHYLFORMAMIDE IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1980-07-08 US disclosed
US-4211723-A PHOSGENE, SULFOBENZOIC ACID, DIMETHYLFORMAMIDE IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1980-07-08 US disclosed
US-4057555-A FROM PHOSGENE AND O-SULFOBENZOIC ACID, DIMETHYLFORMAMIDE, ALCOHOL, AMMONIA IHARA CHEMICAL INDUSTRY CO., LTD. (JA) 1977-11-08 US disclosed
US-4057555-A FROM PHOSGENE AND O-SULFOBENZOIC ACID, DIMETHYLFORMAMIDE, ALCOHOL, AMMONIA IHARA CHEMICAL INDUSTRY CO., LTD. (JA) 1977-11-08 US disclosed
JP-S5262241-A PREPARATION OF CHLOROSULFONYLBENZOYL CHLORIDES IHARA CHEM IND CO LTD 1977-05-23 JP disclosed