Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20679612 | 1.00 | TSHR (0.51) | TSHRALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL29678256 | 0.86 | TSHR (0.59) | TSHRALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL242212 | 0.86 | TSHR (0.59) | TSHRALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL14706934 | 0.84 | ERCC1 (0.58) | ALDH1A1HTTSMN1; SMN2MITFNPC1 | |
| SCHEMBL4002460 | 0.83 | TSHR (0.73) | TSHRALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL21663705 | 0.83 | TSHR (0.47) | TSHRALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL31023418 | 0.83 | TSHR (0.73) | TSHRALDH1A1HTTSMN1; SMN2NPC1 | |
| SCHEMBL29103846 | 0.81 | GSTO1 (0.54) | TSHRALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL4010685 | 0.81 | POLB (0.54) | TSHRALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL30149351 | 0.81 | GSTO1 (0.54) | TSHRALDH1A1HTTSMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111615388-B | Immunotherapeutic agent for cancer | 斯汀格瑞治疗股份有限公司 | 2023-11-14 | — | — | CN | disclosed |