Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29825485 | 0.89 | PTGS2 (0.46) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL17064703 | 0.89 | PTGS2 (0.46) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL23358701 | 0.88 | PTGS1 (0.53) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL950143 | 0.88 | PTGS1 (0.64) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL7315950 | 0.87 | ALDH1A1 (0.56) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL15919511 | 0.87 | PTGS1 (0.49) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL17064914 | 0.87 | PTGS1 (0.64) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL25873702 | 0.87 | ALDH1A1 (0.56) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL2000610 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL24467972 | 0.84 | PDPK1 (0.56) | PTGS2PTGS1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543890-A1 | USP1 INHIBITORS AND USES THEREOF | Forma Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119731178-A | USP1 inhibitors and uses thereof | 福马治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2023250084-A1 | USP1 INHIBITORS AND USES THEREOF | FORMA THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |