Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23358701 | 0.88 | PTGS1 (0.53) | ALDH1A1PTGS2PTGS1KDM4EHPGD | |
| SCHEMBL950143 | 0.88 | PTGS1 (0.64) | ALDH1A1PTGS2PTGS1KDM4EHPGD | |
| SCHEMBL14062925 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2PTGS2PTGS1KDM4E | |
| SCHEMBL17064914 | 0.87 | PTGS1 (0.64) | ALDH1A1PTGS2PTGS1KDM4EHPGD | |
| SCHEMBL30677019 | 0.87 | PTGS2 (0.53) | ALDH1A1PTGS2PTGS1KDM4EHPGD | |
| SCHEMBL15919511 | 0.87 | PTGS1 (0.49) | ALDH1A1PTGS2PTGS1KDM4EHPGD | |
| SCHEMBL25873702 | 0.87 | ALDH1A1 (0.56) | ALDH1A1PTGS2PTGS1KDM4EHPGD | |
| SCHEMBL6343163 | 0.85 | PTGS2 (0.67) | PTGS2PTGS1TSHRPDPK1 | |
| SCHEMBL2000610 | 0.84 | PTGS2 (0.67) | ALDH1A1PTGS2PTGS1KDM4EHPGD | |
| SCHEMBL24467972 | 0.84 | PDPK1 (0.56) | ALDH1A1PTGS2PTGS1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | ALDH1A1 211/4885SMN1; SMN2 4665/4885PTGS2 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.