Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19435170 | 0.83 | NPY5R (0.44) | ALDH1A1POLBNPSR1MAPK14RIPK1 | |
| SCHEMBL25184267 | 0.82 | PTGS2 (0.54) | PTGS2MAPTALDH1A1KDM4EPTGS1 | |
| SCHEMBL30677159 | 0.80 | MAPK14 (0.44) | MAPTALDH1A1POLBCDK8NPSR1 | |
| SCHEMBL31546285 | 0.80 | SLC34A1 (0.44) | MAPTALDH1A1NPSR1TDP1RIPK1 | |
| SCHEMBL31546295 | 0.78 | CRACR2A (0.43) | — | |
| SCHEMBL4231163 | 0.75 | MAPT (0.59) | PTGS2MAPTRECQLGAAALDH1A1 | |
| SCHEMBL9910542 | 0.74 | CDK8 (0.55) | MAPTNPC1RAB9ACDK8MAPK14 | |
| SCHEMBL21821553 | 0.71 | SMPD1 (0.49) | PTGS2SMPD1ALDH1A1 | |
| SCHEMBL14314274 | 0.70 | PRKCZ (0.55) | PTGS2POLBCDK8PTGS1MAPK14 | |
| SCHEMBL12847029 | 0.70 | CDK8 (0.44) | PTGS2MAPTRECQLNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543890-A1 | USP1 INHIBITORS AND USES THEREOF | Forma Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119731178-A | USP1 inhibitors and uses thereof | 福马治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2023250084-A1 | USP1 INHIBITORS AND USES THEREOF | FORMA THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |