Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18865512 | 0.84 | KLKB1 (0.49) | MAPK14CYP1A2KLKB1MAPTSTIM1 | |
| SCHEMBL30677147 | 0.80 | PTGS2 (0.41) | MAPK14CDK8MAPTPOLBTDP1 | |
| SCHEMBL30677244 | 0.80 | CRACR2A (0.43) | MAPK14ORAI1 | |
| SCHEMBL2288170 | 0.78 | MAPT (0.53) | CYP1A2MAPTPOLBTDP1L3MBTL1 | |
| SCHEMBL31546285 | 0.77 | SLC34A1 (0.44) | MAPTTDP1ALDH1A1NPSR1 | |
| SCHEMBL31625143 | 0.76 | KLKB1 (0.48) | MAPK14KLKB1ORAI1 | |
| SCHEMBL31625145 | 0.76 | KLKB1 (0.48) | MAPK14KLKB1ORAI1 | |
| SCHEMBL18865795 | 0.75 | CYP1A2 (0.43) | MAPK14CYP1A2MAPTPOLBL3MBTL1 | |
| SCHEMBL30607571 | 0.74 | F10 (0.40) | MAPK14KLKB1MAPTALDH1A1 | |
| SCHEMBL21821540 | 0.73 | SMN1; SMN2 (0.45) | MAPTTDP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543890-A1 | USP1 INHIBITORS AND USES THEREOF | Forma Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| CN-119731178-A | USP1 inhibitors and uses thereof | 福马治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-2023250084-A1 | USP1 INHIBITORS AND USES THEREOF | FORMA THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |