Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183274 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1KDM4AKDM4BKDM5C | |
| SCHEMBL30987232 | 0.74 | MPO (0.41) | KDM4EALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL11611665 | 0.69 | IP6K1 (0.44) | ALDH1A1HTTMAPK1 | |
| SCHEMBL422208 | 0.69 | MKNK1 (0.42) | KDM4EALDH1A1GAA | |
| SCHEMBL23242476 | 0.68 | HTT (0.50) | KDM4EALDH1A1ADORA2ALMNAHTT | |
| SCHEMBL7311364 | 0.67 | ALDH1A1 (0.47) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28870957 | 0.67 | HTT (0.62) | KDM4EALDH1A1ADORA2ALMNAHTT | |
| SCHEMBL4875480 | 0.66 | KDM4E (0.36) | KDM4EALDH1A1KDM4AKDM4BKDM5C | |
| SCHEMBL20576697 | 0.66 | ADORA2A (0.53) | KDM4EALDH1A1ADORA2ALMNAADORA3 | |
| SCHEMBL30387071 | 0.66 | ADORA2A (0.57) | KDM4EALDH1A1ADORA2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024014885-A1 | NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF | 일동제약(주) | 2024-01-18 | — | — | WO | disclosed |