SCHEMBL30677293

SCHEMBL30677293

Cc1ccccc1C(=O)NN

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.60
CTSD P07339 2/20 0.58
P2RX7 Q99572 1/20 0.56
SMN1; SMN2 Q16637 4/20 0.55
GAA P10253 1/20 0.54
ERCC5 P28715 1/20 0.53
FEN1 P39748 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
POLB P06746 1/20 0.53
TYK2 P29597 1/20 0.53
ALDH1A1 P00352 2/20 0.53
MAPK1 P28482 1/20 0.53
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1128274 1.00 HPGD (0.60) HPGDCTSDP2RX7SMN1; SMN2GAA
Hydrochloric Acid SCHEMBL27561051 0.98 HPGD (0.58) HPGDCTSDP2RX7SMN1; SMN2GAA
Water SCHEMBL8856490 0.86 HPGD (0.47) HPGDCTSDP2RX7SMN1; SMN2GAA
SCHEMBL1827983 0.84 CTSD (0.51) HPGDCTSDP2RX7SMN1; SMN2GAA
SCHEMBL30547074 0.84 CTSD (0.63) CTSDP2RX7GAACA1CA2
SCHEMBL239328 0.84 CTSD (0.63) CTSDP2RX7GAACA1CA2
SCHEMBL7868556 0.83 ALDH1A1 (0.62) HPGDCTSDP2RX7SMN1; SMN2GAA
SCHEMBL668153 0.83 P2RX7 (0.53) CTSDP2RX7CA1CA2CA9
SCHEMBL2650229 0.82 POLB (0.72) HPGDSMN1; SMN2GAAPOLBTYK2
SCHEMBL3140037 0.82 HPGD (0.64) HPGDSMN1; SMN2POLBTYK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014885-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF 일동제약(주) 2024-01-18 WO disclosed