SCHEMBL160073

SCHEMBL160073

ONc1ncnc2[nH]cnc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.35
CYP1A2 P05177 2/20 0.34
HIF1A Q16665 1/20 0.34
MKNK1 Q9BUB5 2/20 0.33
EGFR P00533 2/20 0.32
CDK2 P24941 1/20 0.32
HTT P42858 4/20 0.32
LMNA P02545 4/20 0.31
PI4KA P42356 2/20 0.31
PI4K2B Q8TCG2 2/20 0.31
PI4K2A Q9BTU6 2/20 0.31
PI4KB Q9UBF8 2/20 0.31
DRD3 P35462 1/20 0.31
XDH P47989 1/20 0.31
LRRK2 Q5S007 1/20 0.31
BRD4 O60885 1/20 0.31
PAK1 Q13153 1/20 0.31
TTBK1 Q5TCY1 1/20 0.31
TTBK2 Q6IQ55 1/20 0.31
HDAC1 Q13547 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11591791 0.81 HTT (0.33) CYP3A4CYP1A2HIF1AMKNK1EGFR
SCHEMBL2116843 0.81 PDPK1 (0.33) CYP3A4CYP1A2HIF1AMKNK1EGFR
SCHEMBL22892194 0.79 CSNK2A1 (0.33) CYP3A4CYP1A2HIF1AMKNK1EGFR
SCHEMBL21913 0.79 YTHDC1 (0.47) CYP3A4CYP1A2HIF1ACDK2HTT
SCHEMBL18640373 0.79 CYP3A4 (0.42) CYP3A4CYP1A2HIF1ACDK2HTT
SCHEMBL6272986 0.78 YTHDC1 (0.46) CYP3A4CYP1A2HIF1ACDK2HTT
SCHEMBL10918759 0.78 YTHDC1 (0.46) CYP3A4CYP1A2HIF1ACDK2HTT
SCHEMBL22118770 0.77 BRD4 (0.40) MKNK1EGFRBRD4TOP2ABRAF
SCHEMBL5437606 0.77 MKNK1 (0.38) MKNK1EGFRXDHBRD4TOP2A
SCHEMBL405822 0.76 PDPK1 (0.34) CYP3A4CYP1A2HIF1AEGFRCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
WO-2025024123-A1 NOVEL CITICOLINE DERIVATIVES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-30 WO claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-9677067-B2 Compositions and methods for synthetic gene assembly Twist Bioscience Corporation (US) 2017-06-13 US claimed
US-20170159044-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation 2017-06-08 US claimed
US-20160264958-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation 2016-09-15 US claimed
WO-2016126987-A1 COMPOSITIONS AND METHODS FOR SYNTHETIC GENE ASSEMBLY Twist Bioscience Corporation (US) 2016-08-11 WO claimed
EP-2694524-B1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES US HEALTH (US) 2016-05-18 EP claimed
US-9284343-B2 2′-O-aminooxymethyl nucleoside derivatives for use in the synthesis and modification of nucleosides, nucleotides and oligonucleotides THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2016-03-15 US claimed
EP-2567964-B1 Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection AGILENT TECHNOLOGIES INC (US) 2015-02-11 EP claimed
US-20140051846-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES TheUnited ofAmerica,asrepresentedbythe Secre -tary,Department ofHealthand Human Service (US) 2014-02-20 US claimed
EP-2694524-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES The U.S.A. As Represented By The Secretary, Department Of Health And Human Services (US) 2014-02-12 EP claimed
WO-2012138530-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2012-10-11 WO claimed
US-7807356-B2 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. (US) 2010-10-05 US claimed
US-7524942-B2 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. (US) 2009-04-28 US claimed
US-20080124708-A1 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. 2008-05-29 US claimed
US-20070212697-A1 Labeled nucleotide composition AGILENT TECHNOLOGIES, INC. 2007-09-13 US claimed
EP-4748940-A2 DE NOVO SYNTHESISED GENE LIBRARIES Twist Bioscience Corporation (US) 2026-05-27 EP disclosed
EP-0671928-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1995-09-20 EP disclosed
WO-1994006451-A1 SYNTHESIS OF N-SUBSTITUTED OLIGOMERS CHIRON CORPORATION (US) 1994-03-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080124708-A1 Labeled nucleotide composition RNGTT, RNMT, NOP2 CYP3A4 3828/4885CYP1A2 3227/4885HIF1A 4231/4885
US-20070212697-A1 Labeled nucleotide composition RNGTT, RNMT, NOP2 CYP3A4 3828/4885CYP1A2 3227/4885HIF1A 4231/4885
US-20140051846-A1 2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES NSUN2, RNGTT, RNMT CYP3A4 3895/4885CYP1A2 3150/4885HIF1A 3748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.