SCHEMBL3067943

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10181050	0.92	STAT3 (0.59)	STAT3PIK3CAPRKAA2
	SCHEMBL3056599	0.92	STAT3 (0.46)	MAPTHTTSTAT3SCN9AGAA
	SCHEMBL3055461	0.90	SCN9A (0.54)	STAT3SCN9ASCN7AKCNH2SCN5A
	SCHEMBL3062169	0.90	SCN9A (0.47)	STAT3SCN9ASCN7AKCNH2SCN5A
	SCHEMBL3050846	0.89	SCN9A (0.47)	MAPTHTTSTAT3SCN9APIK3CA
	Maleic Acid SCHEMBL3056841	0.89	STAT3 (0.56)	STAT3PIK3CAPRKAA2
	Fumaric Acid SCHEMBL3056843	0.89	STAT3 (0.56)	STAT3PIK3CAPRKAA2
	Bromide SCHEMBL3056616	0.89	STAT3 (0.52)	STAT3PIK3CAPRKAA2
	Bromide SCHEMBL3056975	0.89	STAT3 (0.57)	STAT3PIK3CAPRKAA2
	SCHEMBL3052050	0.89	SCN9A (0.50)	STAT3SCN9ASCN7AKCNH2SCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.