Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | MPL | P40238 | 3/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26704175 | 0.87 | KIF11 (0.73) | KIF11TRIM24TRIM33CA12CA1 | |
| SCHEMBL30679640 | 0.85 | KIF11 (0.75) | KIF11MPLKMOARDRD1 | |
| SCHEMBL3831122 | 0.83 | TRIM24 (0.46) | KIF11TRIM24TRIM33CA12CA1 | |
| SCHEMBL16552545 | 0.83 | HSD17B1 (0.54) | KIF11TRIM24TRIM33CA12CA1 | |
| SCHEMBL30861658 | 0.83 | TRIM24 (0.46) | KIF11TRIM24TRIM33CA12CA1 | |
| SCHEMBL18002387 | 0.81 | KIF11 (0.53) | KIF11MPLKMOAR | |
| SCHEMBL5735574 | 0.81 | TRIM24 (0.54) | KIF11TRIM24TRIM33CA12CA1 | |
| SCHEMBL10299815 | 0.81 | KIF11 (0.58) | KIF11MPLKMOARALDH1A1 | |
| SCHEMBL67628 | 0.81 | KIF11 (0.58) | KIF11MPLKMOARALDH1A1 | |
| SCHEMBL18002827 | 0.81 | KIF11 (0.47) | KIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430570-A | Rhodamine acetic acid compound, and pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-01-23 | — | — | CN | disclosed |