Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 15/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TACR2 | P21452 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699666 | 0.88 | CCR5 (0.63) | CCR5SLC6A4STAT3NPSR1TACR2 | |
| SCHEMBL29689869 | 0.88 | CCR5 (0.63) | CCR5SLC6A4STAT3NPSR1TACR2 | |
| SCHEMBL20535668 | 0.88 | TACR2 (0.54) | CCR5SLC6A4STAT3TACR2 | |
| SCHEMBL4427861 | 0.85 | CCR5 (0.50) | CCR5SLC6A4 | |
| SCHEMBL31001958 | 0.83 | HDAC8 (0.54) | CCR5NPSR1 | |
| SCHEMBL29227218 | 0.82 | CCR5 (0.56) | CCR5SLC6A4STAT3NPSR1TACR2 | |
| SCHEMBL31167125 | 0.82 | LMNA (0.45) | CCR5 | |
| SCHEMBL14075999 | 0.82 | CCR5 (0.48) | CCR5 | |
| SCHEMBL13580768 | 0.82 | PTGER1 (0.48) | CCR5NPSR1 | |
| SCHEMBL20535587 | 0.80 | TACR2 (0.52) | CCR5TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117430570-A | Rhodamine acetic acid compound, and pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-01-23 | — | — | CN | disclosed |