SCHEMBL3067968

SCHEMBL3067968

O=C1c2ccccc2C(=O)c2c1ccc(O)c2OF

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.61
MEN1 O00255 6/20 0.61
KMT2A Q03164 6/20 0.61
MCL1 Q07820 6/20 0.61
ALDH1A1 P00352 6/20 0.61
MAOA P21397 6/20 0.61
MAPK1 P28482 4/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
BCL2 P10415 4/20 0.61
HPGD P15428 4/20 0.61
ALOX15 P16050 3/20 0.61
HSD17B10 Q99714 3/20 0.61
KDM4E B2RXH2 2/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX12 P18054 2/20 0.61
RECQL P46063 2/20 0.61
DAPK1 P53355 2/20 0.61
CYP1B1 Q16678 2/20 0.61
APEX1 P27695 1/20 0.61
TDP1 Q9NUW8 4/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1426442 0.84 SMN1; SMN2 (0.70) MAPTMEN1KMT2AMCL1ALDH1A1
SCHEMBL4249550 0.84 MAPT (0.62) MAPTMEN1KMT2AMCL1ALDH1A1
SCHEMBL29906115 0.84 SMN1; SMN2 (0.70) MAPTMEN1KMT2AMCL1ALDH1A1
SCHEMBL3242518 0.80 MAPT (0.57) MAPTMEN1KMT2AMCL1ALDH1A1
SCHEMBL18932156 0.80 MAPT (0.57) MAPTMEN1KMT2AMCL1ALDH1A1
SCHEMBL11357255 0.80 MAPT (0.57) MAPTMEN1KMT2AMCL1ALDH1A1
SCHEMBL1574140 0.79 MAPT (0.56) MAPTMEN1KMT2AMCL1ALDH1A1
SCHEMBL3297348 0.78 MAPT (0.54) MAPTMEN1KMT2AMCL1ALDH1A1
Athraquinones A SCHEMBL4972786 0.76 MAPT (1.00) MAPTMEN1KMT2AMCL1ALDH1A1
Athraquinones A SCHEMBL18614 0.76 MAPT (1.00) MAPTMEN1KMT2AMCL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115165866-A Simulated radioactivity 89 Zr marked cold marking method and reagent kit 益诺思生物技术南通有限公司 2022-10-11 CN claimed
CN-114088693-A Simulated radioactivity18F-labeled cold labeling method and kit 益诺思生物技术南通有限公司 2022-02-25 CN claimed
CN-118032961-A Method for detecting illegal additives of cordyceps sinensis 广州市药品检验所 2024-05-14 CN disclosed
CN-115165866-A Simulated radioactivity 89 Zr marked cold marking method and reagent kit 益诺思生物技术南通有限公司 2022-10-11 CN disclosed
CN-114088693-A Simulated radioactivity18F-labeled cold labeling method and kit 益诺思生物技术南通有限公司 2022-02-25 CN disclosed
US-10825580-B2 Compositions for compounding, extrusion and melt processing of foamable and cellular halogen-free polymers CABLE COMPONENTS GROUP, LLC (US) 2020-11-03 US disclosed
EP-3216030-B1 COMPOSITIONS FOR COMPOUNDING, EXTRUSION AND MELT PROCESSING OF FOAMABLE AND CELLULAR HALOGEN-FREE POLYMERS CABLE COMPONENTS GROUP LLC (US) 2020-05-06 EP disclosed
US-20190004265-A1 COMPOSITIONS FOR COMPOUNDING, EXTRUSION AND MELT PROCESSING OF FOAMABLE AND CELLULAR POLYMERS CABLE COMPONENTS GROUP, LLC 2019-01-03 US disclosed
US-20180322985-A1 COMPOSITIONS FOR COMPOUNDING, EXTRUSION AND MELT PROCESSING OF FOAMABLE AND CELLULAR HALOGEN-FREE POLYMERS CABLE COMPONENTS GROUP, LLC 2018-11-08 US disclosed
US-10031301-B2 Compositions for compounding, extrusion, and melt processing of foamable and cellular polymers CABLE COMPONENTS GROUP, LLC (US) 2018-07-24 US disclosed
US-10032542-B2 Compositions for compounding, extrusion and melt processing of foamable and cellular halogen-free polymers CABLE COMPONENTS GROUP, LLC (US) 2018-07-24 US disclosed
US-20140088308-A1 Fluoride-Releasing Compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2014-03-27 US disclosed
US-8598381-B2 Fluoride-releasing compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2013-12-03 US disclosed
US-20120264939-A1 Fluoride-Releasing Compositions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-10-18 US disclosed
US-8217173-B2 Fluoride-releasing compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2012-07-10 US disclosed
US-20100261902-A1 Fluoride-Releasing Compositions BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) 2010-10-14 US disclosed
WO-2008100907-A2 FLUORIDE-RELEASING COMPOSITIONS BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND ARGRICULTURAL AND MECHANICAL COLLEGE (US) 2008-08-21 WO disclosed
US-6703518-B1 DENTISTRY BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE 2004-03-09 US disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
US-3957438-A Detecting fluorite in a solid rock sample LOST RIVER MINING CORPORATION LIMITED (CA) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140088308-A1 Fluoride-Releasing Compositions CHERP, ORAI1, CAD MAPT 3503/4885MEN1 1176/4885KMT2A 3397/4885
US-20120264939-A1 Fluoride-Releasing Compositions CHERP, ORAI1, CAD MAPT 3503/4885MEN1 1176/4885KMT2A 3397/4885
US-20100261902-A1 Fluoride-Releasing Compositions CHERP, ORAI1, CAD MAPT 3503/4885MEN1 1176/4885KMT2A 3397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.