Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 6/20 | 0.62 |
| ▸ | BCL2 | P10415 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1426442 | 1.00 | SMN1; SMN2 (0.70) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL19462002 | 0.88 | MAOA (0.66) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL19462005 | 0.86 | MAOA (0.67) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL4249550 | 0.86 | MAPT (0.62) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL2461009 | 0.85 | RAB9A (0.53) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL18932156 | 0.85 | MAPT (0.57) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL3067968 | 0.84 | MAPT (0.61) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL19438363 | 0.83 | LCK (0.55) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL3419749 | 0.82 | SMN1; SMN2 (0.70) | SMN1; SMN2RAB9ANPC1MAPTMEN1 | |
| SCHEMBL496978 | 0.82 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240315965-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2024-09-26 | — | — | US | claimed |
| WO-2022182523-A1 | COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | claimed |
| WO-2022182527-A1 | COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS | Natural Extraction Systems, LLC (US) | 2022-09-01 | — | — | WO | disclosed |