Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31299007 | 1.00 | ABCB1 (0.54) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8067076 | 0.87 | ITGB3 (0.59) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL2968658 | 0.87 | ITGB3 (0.59) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL31739224 | 0.87 | ITGB3 (0.59) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL2494968 | 0.87 | ITGB3 (0.59) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL26654521 | 0.86 | ITGB3 (0.58) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL26654515 | 0.86 | ITGB3 (0.58) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL22457646 | 0.84 | ABCB1 (0.62) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL25183099 | 0.84 | ITGB3 (0.57) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL30688544 | 0.82 | ITGB3 (0.58) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4520748-A1 | METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-03-12 | — | — | EP | disclosed |
| CN-119156373-A | Method for producing salts of amino acids or salts of peptide compounds or solvates of any of the salts comprising a lithium salt precipitation step | 中外制药株式会社 | 2024-12-17 | — | — | CN | disclosed |
| WO-2023219152-A1 | METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP | 中外製薬株式会社 | 2023-11-16 | — | — | WO | disclosed |