Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31739224 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL2494968 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL8067076 | 1.00 | ITGB3 (0.59) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL26654521 | 0.98 | ITGB3 (0.58) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL26654515 | 0.98 | ITGB3 (0.58) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL30688507 | 0.94 | ITGB3 (0.58) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL30688544 | 0.94 | ITGB3 (0.58) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL30688553 | 0.94 | ITGB3 (0.58) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL25183099 | 0.93 | ITGB3 (0.57) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 | |
| SCHEMBL25186398 | 0.92 | ITGB3 (0.53) | ITGB3ITGA2BABCB1ALDH1A1CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767811-B2 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | BRANDEIS UNIVERSITY (US) | 2010-08-03 | — | — | US | disclosed |
| US-20060293536-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | BRANDEIS UNIVERSITY (US) | 2006-12-28 | — | — | US | disclosed |
| US-7057038-B2 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | BRANDEIS UNIVERSITY (US) | 2006-06-06 | — | — | US | disclosed |
| EP-1419125-A4 | KINETIC RESOLUTIONS OF CHIRAT 3- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | UNIV BRANDEIS (US) | 2005-03-23 | — | — | EP | disclosed |
| US-20050020849-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | DENG LI (US) | 2005-01-27 | — | — | US | disclosed |
| US-6743914-B2 | USING TERTIARY AMINE CATALYST | BRANDEIS UNIVERSITY | 2004-06-01 | — | — | US | disclosed |
| EP-1419125-A1 | KINETIC RESOLUTIONS OF CHIRAT 3- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | Brandeis University (US) | 2004-05-19 | — | — | EP | disclosed |
| EP-1305270-B1 | KINETIC RESOLUTIONS OF CHIRAL 2- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | UNIV BRANDEIS (US) | 2004-04-14 | — | — | EP | disclosed |
| US-20030166963-A1 | Kinetic resolutions of chiral 2-and 3-substituted carboxylic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-09-04 | — | — | US | disclosed |
| US-6562967-B2 | Drug screening; purity | BRANDEIS UNIVERSITY | 2003-05-13 | — | — | US | disclosed |
| EP-1305270-A1 | KINETIC RESOLUTIONS OF CHIRAL 2- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | Brandeis University (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2003011799-A1 | KINETIC RESOLUTIONS OF CHIRAT 3- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | BRANDEIS UNIVERSITY (US) | 2003-02-13 | — | — | WO | disclosed |
| US-20020165393-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-11-07 | — | — | US | disclosed |
| US-20020151744-A1 | Kinetic resolutions of chiral 2-and-3-substituted carboxylic acids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-10-17 | — | — | US | disclosed |
| WO-2002010096-A1 | KINETIC RESOLUTIONS OF CHIRAL 2- AND 3-SUBSTITUTED CARBOXYLIC ACIDS | BRANDEIS UNIVERSITY (US) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020165393-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | ADH5, ADH1C, TST | ITGB3 1780/4885ITGA2B 3170/4885ABCB1 4828/4885 |
| US-20050020849-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | ADH5, ADH1C, TST | ITGB3 1008/4885ITGA2B 2236/4885ABCB1 4760/4885 |
| US-20060293536-A1 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids | ADH5, ADH1C, TST | ITGB3 1008/4885ITGA2B 2236/4885ABCB1 4760/4885 |
| US-20030166963-A1 | Kinetic resolutions of chiral 2-and 3-substituted carboxylic acids | ADH5, ADH1C, TST | ITGB3 1859/4885ITGA2B 3225/4885ABCB1 4832/4885 |
| US-20020151744-A1 | Kinetic resolutions of chiral 2-and-3-substituted carboxylic acids | ADH5, ADH1C, TST | ITGB3 1272/4885ITGA2B 2689/4885ABCB1 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.