Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL30679693 | 1.00 | ABCB1 (0.54) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL8067076 | 0.87 | ITGB3 (0.59) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL2968658 | 0.87 | ITGB3 (0.59) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL31739224 | 0.87 | ITGB3 (0.59) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL2494968 | 0.87 | ITGB3 (0.59) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL26654521 | 0.86 | ITGB3 (0.58) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL26654515 | 0.86 | ITGB3 (0.58) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL22457646 | 0.84 | ABCB1 (0.62) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL25183099 | 0.84 | ITGB3 (0.57) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 | |
| SCHEMBL30688544 | 0.82 | ITGB3 (0.58) | ABCB1P2RX7ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250368680-A1 | METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2025-12-04 | — | — | US | disclosed |
| CN-119156373-A | Method for producing salts of amino acids or salts of peptide compounds or solvates of any of the salts comprising a lithium salt precipitation step | 中外制药株式会社 | 2024-12-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250368680-A1 | METHOD FOR PRODUCING SALT OF AMINO ACID OR SALT OF PEPTIDE COMPOUND OR SOLVATE OF EITHER ONE OF SAID SALTS COMPRISING LITHIUM SALT PRECIPITATION STEP | NPPA, DNPEP, NPEPPS | ABCB1 4843/4885P2RX7 4606/4885ITGB3 4488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.