Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8260694 | 0.80 | DRD2 (0.35) | — | |
| SCHEMBL10315548 | 0.74 | — | — | |
| SCHEMBL22342840 | 0.69 | SLC9A1 (0.44) | — | |
| SCHEMBL29750144 | 0.69 | PNMT (0.37) | — | |
| SCHEMBL10139767 | 0.69 | PNMT (0.37) | — | |
| SCHEMBL9156518 | 0.66 | KDM4E (0.42) | ACHE | |
| SCHEMBL13725248 | 0.66 | PDE3B (0.41) | ACHE | |
| SCHEMBL30101526 | 0.65 | HTR2C (0.36) | — | |
| SCHEMBL17984826 | 0.65 | HTR2C (0.36) | — | |
| SCHEMBL1528492 | 0.64 | HTR2C (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514789-A1 | <SUP2/>? <SUB2/>?V?BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA1.8 FOR THE TREATMENT OF PAIN | SiteOne Therapeutics, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023211990-A1 | BICYCLIC HETEROCYCLIC AMIDE INHIBITORS OF NA V1.8 FOR THE TREATMENT OF PAIN | SITEONE THERAPEUTICS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |