Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781047 | 0.82 | L3MBTL3 (0.60) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BKDM1A | |
| SCHEMBL26683504 | 0.82 | L3MBTL3 (0.40) | L3MBTL3L3MBTL1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3104303 | 0.80 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BMEN1 | |
| SCHEMBL4550247 | 0.80 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1SMN1; SMN2 | |
| SCHEMBL8679035 | 0.79 | L3MBTL3 (0.53) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BMEN1 | |
| SCHEMBL2232096 | 0.79 | L3MBTL3 (0.38) | L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL8362221 | 0.78 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BMEN1 | |
| SCHEMBL22878132 | 0.78 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BMEN1 | |
| SCHEMBL20842232 | 0.78 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BMEN1 | |
| SCHEMBL425964 | 0.78 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1CDYLCDY1; CDY1BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | disclosed |
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |
| EP-3567041-A9 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2022-04-20 | — | — | EP | disclosed |
| US-10874670-B2 | Substituted fused heteroaromatic compounds as kinase inhibitors and the use thereof | IMPACT THERAPEUTICS, INC. (CN) | 2020-12-29 | — | — | US | disclosed |
| EP-3567041-A1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | Impact Therapeutics, Inc (CN) | 2019-11-13 | — | — | EP | disclosed |
| US-8541406-B2 | Thiadiazole derivatives for the treatment of neurodegenerative diseases | NV REMYND (BE) | 2013-09-24 | — | — | US | disclosed |
| US-20100261707-A9 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | NV REMYND (BE) | 2010-10-14 | — | — | US | disclosed |
| US-20090233911-A2 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | NV REMYND (BE) | 2009-09-17 | — | — | US | disclosed |
| US-20090054410-A1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | NV REMYND (BE) | 2009-02-26 | — | — | US | disclosed |
| EP-1022277-B1 | NEW TAXANE DERIVATIVES | YAKULT HONSHA KK (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6268381-B1 | Taxane derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2001-07-31 | — | — | US | disclosed |
| US-6136808-A | ANTITUMOR AGENTS FROM PLANTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1044971-A1 | TAXANE DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-10-18 | — | — | EP | disclosed |
| EP-1022277-A1 | NEW TAXANE DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-07-26 | — | — | EP | disclosed |
| US-6025385-A | HIGH SOLUBILITY IN WATER AND ALSO HAS EXCELLENT ANTITUMOR ACTIVITIES. | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2000-02-15 | — | — | US | disclosed |
| EP-0930309-A1 | TAXANE DERIVATIVES AND DRUGS CONTAINING THE SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1999-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233911-A2 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PARK7 | L3MBTL3 901/4885L3MBTL1 791/4885CDYL 4061/4885 |
| US-10874670-B2 | Substituted fused heteroaromatic compounds as kinase inhibitors and the use thereof | CHEK1, CHEK2, CDK1 | L3MBTL3 788/4885L3MBTL1 712/4885CDYL 2719/4885 |
| US-20100261707-A9 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PARK7 | L3MBTL3 901/4885L3MBTL1 791/4885CDYL 4061/4885 |
| US-20090054410-A1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PARK7 | L3MBTL3 901/4885L3MBTL1 791/4885CDYL 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.