Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28412458 | 1.00 | HPGD (0.35) | HPGDALDH1A1KDM4EUSP2PRNP | |
| SCHEMBL20389658 | 0.78 | CYP2C19 (0.37) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL16341884 | 0.76 | KDM4E (0.46) | HPGDALDH1A1KDM4ESMN1; SMN2MAPT | |
| SCHEMBL6865122 | 0.74 | HTR2A (0.34) | HPGDALDH1A1KDM4EUSP2PRNP | |
| SCHEMBL16476633 | 0.73 | KDM4E (0.33) | ALDH1A1KDM4EUSP2HSD17B10TDP1 | |
| SCHEMBL14769541 | 0.72 | AHR (0.35) | KDM4EUSP2SMN1; SMN2NPC1 | |
| SCHEMBL15017289 | 0.71 | JAK1 (0.36) | — | |
| SCHEMBL15016940 | 0.71 | ADORA3 (0.33) | ALDH1A1ADORA3ADORA1 | |
| SCHEMBL29564268 | 0.70 | CYP1A2 (0.35) | — | |
| SCHEMBL16052502 | 0.70 | CYP1A2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264959-A1 | SUBSTITUTED PYRAZOLOPYRIDINES AS PHOSPHOINOSIDIDE KINASE (PIK) MODULATORS | RECURSION PHARMACEUTICALS, INC. (US) | 2025-12-26 | — | — | WO | disclosed |
| CN-111153899-B | Substituted pyridine compound, preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-12-01 | — | — | CN | disclosed |