Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26931827 | 1.00 | CHEK1 (0.32) | CHEK1 | |
| SCHEMBL26931989 | 0.77 | DUT (0.30) | — | |
| SCHEMBL30683062 | 0.77 | DUT (0.30) | — | |
| SCHEMBL30542289 | 0.76 | PLCG1 (0.40) | — | |
| SCHEMBL20944147 | 0.75 | GRM5 (0.42) | CHEK1 | |
| SCHEMBL30967300 | 0.75 | HPGD (0.39) | — | |
| SCHEMBL30967302 | 0.75 | HPGD (0.39) | — | |
| SCHEMBL19776346 | 0.72 | CA12 (0.37) | — | |
| SCHEMBL1629163 | 0.72 | USP8 (0.38) | CHEK1 | |
| SCHEMBL20944096 | 0.72 | ALDH1A1 (0.39) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |