SCHEMBL30683062

SCHEMBL30683062

CC(C)(C)[Si](C)(C)OCCOc1cc(Br)cnc1CN

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26931989 1.00 DUT (0.30) DUTCA12CA1CA2CA9
SCHEMBL26931975 0.79 RAB9A (0.35)
SCHEMBL26931827 0.77 CHEK1 (0.32)
SCHEMBL30683058 0.77 CHEK1 (0.32)
SCHEMBL30683066 0.77 AAK1 (0.39)
SCHEMBL30967302 0.76 HPGD (0.39) DUT
SCHEMBL30967300 0.76 HPGD (0.39) DUT
SCHEMBL29950898 0.73 AGXT (0.32)
SCHEMBL28878932 0.73 AGXT (0.32)
SCHEMBL19776346 0.73 CA12 (0.37) DUTCA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023239645-A1 SMARCA DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2023-12-14 WO disclosed