Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 9/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.35 |
| ▸ | ILK | Q13418 | 3/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24838775 | 0.89 | EGLN1 (0.38) | EGLN1L3MBTL1LMNANAMPTPRMT5 | |
| SCHEMBL26932140 | 0.88 | PRMT5 (0.34) | EGLN1L3MBTL1NAMPTPRMT5WDR77 | |
| SCHEMBL30683019 | 0.88 | PRMT5 (0.34) | EGLN1L3MBTL1NAMPTPRMT5WDR77 | |
| SCHEMBL30683043 | 0.86 | BRD4 (0.37) | BRD4EGLN1L3MBTL1SYKNAMPT | |
| SCHEMBL26931822 | 0.85 | EGLN1 (0.41) | EGLN1EGFRERBB2ILKSYK | |
| SCHEMBL30683031 | 0.83 | AAK1 (0.41) | BRD4L3MBTL1SYKLMNAAAK1 | |
| SCHEMBL25627338 | 0.81 | PRMT5 (0.34) | EGLN1L3MBTL1LMNAPRMT5WDR77 | |
| SCHEMBL30178894 | 0.76 | CA12 (0.37) | BRD4L3MBTL1ABCB1KDM4A | |
| SCHEMBL24837853 | 0.76 | CA12 (0.37) | BRD4L3MBTL1ABCB1KDM4A | |
| SCHEMBL30683098 | 0.76 | GABRA1 (0.36) | L3MBTL1NAMPTPRMT5WDR77KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023239645-A1 | SMARCA DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |