Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | STK17B | O94768 | 1/20 | 0.35 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26686903 | 0.93 | KDM4E (0.42) | KDM4EMAPTNPSR1DRD2ADORA3 | |
| SCHEMBL30685675 | 0.86 | KDM4E (0.39) | KDM4EMAPTNPSR1DRD2ADORA3 | |
| SCHEMBL9941094 | 0.86 | KDM4E (0.39) | KDM4EMAPTNPSR1DRD2ADORA3 | |
| SCHEMBL30685674 | 0.84 | KDM4E (0.38) | KDM4EMAPTNPSR1DRD2ADORA3 | |
| SCHEMBL26686685 | 0.83 | ALDH1A1 (0.34) | KDM4EMAPTNPSR1ADORA3ADORA2A | |
| SCHEMBL30964223 | 0.81 | ADORA3 (0.38) | KDM4EMAPTNPSR1DRD2ADORA3 | |
| SCHEMBL16700419 | 0.81 | ADORA3 (0.38) | KDM4EMAPTNPSR1DRD2ADORA3 | |
| SCHEMBL18833462 | 0.77 | ADORA3 (0.41) | KDM4EMAPTNPSR1DRD2ADORA3 | |
| SCHEMBL30685706 | 0.76 | ALDH1A1 (0.41) | KDM4EMAPTNPSR1ADORA3ADORA2A | |
| SCHEMBL18764922 | 0.76 | PDE4D (0.42) | KDM4EMAPTNPSR1DRD2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279917-A | Piperazine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-12-22 | — | — | CN | disclosed |