SCHEMBL30685706

SCHEMBL30685706

CCOC(=O)c1nn(CCN)c(C(=O)OCC)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
NPC1 O15118 4/20 0.41
RAB9A P51151 3/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
POLB P06746 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
GAA P10253 1/20 0.38
ELANE P08246 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPK1 P28482 2/20 0.38
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
TP53 P04637 1/20 0.37
MAPT P10636 1/20 0.37
XBP1 P17861 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26873124 0.92 TEAD2 (0.40) ALDH1A1NPC1RAB9AKDM4EHSD17B10
Hydrochloric Acid SCHEMBL26686919 0.91 TEAD2 (0.39) ALDH1A1NPC1RAB9AKDM4EHSD17B10
SCHEMBL24687912 0.83 ALDH1A1 (0.41) ALDH1A1NPC1RAB9AKDM4EHSD17B10
SCHEMBL26686907 0.80 ALDH1A1 (0.38) ALDH1A1NPC1RAB9AKDM4EHSD17B10
SCHEMBL30685681 0.80 ALDH1A1 (0.39) ALDH1A1NPC1RAB9AKDM4EHSD17B10
Hydrochloric Acid SCHEMBL26686999 0.79 ALDH1A1 (0.37) ALDH1A1NPC1RAB9AKDM4EHSD17B10
SCHEMBL30685698 0.76 KDM4E (0.39) ALDH1A1NPC1RAB9AKDM4EHPGD
SCHEMBL26686903 0.75 KDM4E (0.42) KDM4EHPGDADORA3ADORA2AGAA
SCHEMBL31667548 0.72 POLB (0.50) ALDH1A1NPC1RAB9AKDM4EHPGD
SCHEMBL28555287 0.72 MAPT (0.49) ALDH1A1NPC1RAB9AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117279917-A Piperazine derivatives and their use in medicine 成都百裕制药股份有限公司 2023-12-22 CN disclosed