SCHEMBL3068892

SCHEMBL3068892

O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1CO)N1CCC(N2CCOC2=O)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 1/20 0.33
VNN1 O95497 1/20 0.33
TYRO3 Q06418 2/20 0.33
MERTK Q12866 2/20 0.33
NPY5R Q15761 1/20 0.32
RBP4 P02753 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3057907 0.90 F10 (0.36) F10VNN1TYRO3MERTKNPY5R
SCHEMBL3063951 0.89 VNN1 (0.34) F10VNN1TYRO3MERTKNPY5R
SCHEMBL3063954 0.89 VNN1 (0.35) F10VNN1TYRO3MERTKNPY5R
SCHEMBL3063831 0.88 ERN1 (0.35) F10VNN1TYRO3MERTKNPY5R
SCHEMBL3074119 0.87 RET (0.33) F10VNN1TYRO3MERTKNPY5R
SCHEMBL3074607 0.87 KDM5A (0.34) F10VNN1TYRO3MERTKNPY5R
SCHEMBL3064153 0.87 VNN1 (0.34) F10VNN1TYRO3MERTKNPY5R
SCHEMBL13090302 0.84 F10 (0.31) F10NPY5R
SCHEMBL3076986 0.82 RBP4 (0.39) F10VNN1NPY5RRBP4
SCHEMBL3076055 0.80 VNN1 (0.32) VNN1TYRO3MERTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100272680-A1 Piperidinyl Cyclic Amido Antiviral Agents BASKARAN SUBRAMANIAN 2010-10-28 US claimed
US-20100272680-A1 Piperidinyl Cyclic Amido Antiviral Agents BASKARAN SUBRAMANIAN 2010-10-28 US disclosed
US-20100272680-A1 Piperidinyl Cyclic Amido Antiviral Agents BASKARAN SUBRAMANIAN 2010-10-28 US disclosed
WO-2010091411-A1 PIPERIDINYL CYCLIC AMIDO ANTIVIRAL AGENTS GLAXOSMITHKLINE LLC (US) 2010-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100272680-A1 Piperidinyl Cyclic Amido Antiviral Agents ZC3HAV1, MAVS, EIF2AK2 F10 2944/4885VNN1 1145/4885TYRO3 3671/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.