Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | KCNT1 | Q5JUK3 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | KCNMB1 | Q16558 | 1/20 | 0.36 |
| ▸ | KCNT2 | Q6UVM3 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689362 | 0.83 | MITF (0.39) | ACACBPPARDPPARATP53MITF | |
| SCHEMBL23588079 | 0.82 | ACACB (0.46) | ACACBTP53MITFNCOA3FFAR1 | |
| SCHEMBL23578576 | 0.80 | RAB9A (0.40) | HDAC4HDAC6PPARATP53MITF | |
| SCHEMBL25804401 | 0.80 | TSHR (0.47) | TP53SCN5ATSHRMAPTSMN1; SMN2 | |
| SCHEMBL23588293 | 0.80 | HTT (0.40) | TP53MITFNCOA3TSHRMAPT | |
| SCHEMBL25807564 | 0.80 | TP53 (0.39) | TP53MITFNCOA3TSHRMAPT | |
| SCHEMBL23588294 | 0.80 | TP53 (0.39) | TP53MITFNCOA3TSHRMAPT | |
| SCHEMBL30689418 | 0.80 | LTA4H (0.41) | TP53MITFNCOA3KCNH2FFAR1 | |
| SCHEMBL23588138 | 0.79 | TP53 (0.37) | TP53MITFNCOA3TSHRMAPT | |
| SCHEMBL23588289 | 0.79 | PPARD (0.46) | PPARDPPARATP53MITFNCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |