Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30689383 | 0.88 | TP53 (0.41) | TP53ACACBMAPTLMNAATM | |
| SCHEMBL30689348 | 0.83 | IP6K1 (0.41) | TP53ACACBLMNAATMALDH1A1 | |
| SCHEMBL30689338 | 0.78 | ACACB (0.36) | TP53NPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL30689312 | 0.78 | FPR2 (0.43) | MAPTTSHRSMN1; SMN2SCN9A | |
| SCHEMBL25802137 | 0.77 | MAPT (0.50) | MAPTLMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL25807565 | 0.76 | TP53 (0.42) | TP53NPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25802125 | 0.76 | MEN1 (0.46) | TP53NPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25802130 | 0.76 | TP53 (0.42) | TP53NPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL25801756 | 0.76 | TSHR (0.55) | NPC1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL23588077 | 0.76 | ACACB (0.52) | TP53NPC1ACACBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543875-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | Sitryx Therapeutics Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023247958-A1 | OXADIAZOLE DERIVATIVES, PREPARATION PROCESS THEREOF AND THEIR USE IN TREATING INFLAMMATORY DISEASES | SITRYX THERAPEUTICS LIMITED (GB) | 2023-12-28 | — | — | WO | disclosed |