Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13509914 | 0.87 | HPGD (0.47) | NR1H2TGFBR1KDM4EPKMHPGD | |
| SCHEMBL13694467 | 0.85 | NR1H2 (0.43) | NR1H2TGFBR1KDM4EPKMMEN1 | |
| SCHEMBL26213031 | 0.85 | NR1H2 (0.43) | NR1H2TGFBR1KDM4EPKMMEN1 | |
| SCHEMBL14678793 | 0.85 | NR1H2 (0.43) | NR1H2TGFBR1KDM4EPKMMEN1 | |
| SCHEMBL14282766 | 0.84 | NR1H2 (0.50) | NR1H2TGFBR1KDM4EPKMMEN1 | |
| SCHEMBL29257891 | 0.80 | NR1H2 (0.60) | NR1H2KDM4EPKMMEN1ALDH1A1 | |
| SCHEMBL14533317 | 0.80 | MEN1 (0.48) | NR1H2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL17075668 | 0.80 | MEN1 (0.48) | NR1H2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30922876 | 0.80 | MEN1 (0.48) | NR1H2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22181202 | 0.79 | NR1H2 (0.51) | NR1H2KDM4EPKMMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250236607-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2025-07-24 | — | — | US | disclosed |
| EP-4499148-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | Ohio State Innovation Foundation (US) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023192534-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250236607-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | CDK9, CDK19, CDKL2 | NR1H2 3420/4885TGFBR1 4344/4885KDM4E 153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.