Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 8/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.55 |
| ▸ | PGR | P06401 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HTR2B | P41595 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 8/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | BLM | P54132 | 4/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068078 | 0.96 | SHBG (0.53) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL3057144 | 0.85 | SHBG (0.58) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL14713210 | 0.85 | SHBG (0.58) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL11508378 | 0.85 | SHBG (0.58) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL3246003 | 0.84 | SHBG (0.57) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL3073418 | 0.83 | SHBG (0.55) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| Potassium Ion SCHEMBL10786275 | 0.83 | SHBG (0.55) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10783197 | 0.83 | NR3C1 (0.55) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL7793950 | 0.82 | SHBG (0.54) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL10959339 | 0.80 | PSEN1 (0.58) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383809-B2 | Process for the preparation of drospirenone | NEWCHEM S.P.A. (IT) | 2013-02-26 | — | — | US | disclosed |
| EP-2019114-B1 | Process for the preparation of Drospirenone | NEWCHEM S P A (IT) | 2010-12-15 | — | — | EP | disclosed |
| US-20100222571-A1 | PROCESS FOR THE PREPARATION OF DROSPIRENONE | NEWCHEM S.P.A. (IT) | 2010-09-02 | — | — | US | disclosed |
| EP-2019114-A1 | Process for the preparation of Drospirenone | Newchem S.p.A. (IT) | 2009-01-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222571-A1 | PROCESS FOR THE PREPARATION OF DROSPIRENONE | CYP17A1, CYP19A1, DHCR7 | SHBG 173/4885NR3C1 311/4885PGR 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.