Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.54 |
| ▸ | PGR | P06401 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3246003 | 0.87 | SHBG (0.57) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL10783197 | 0.86 | NR3C1 (0.55) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL10781408 | 0.85 | PSEN1 (0.52) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL10959339 | 0.85 | PSEN1 (0.58) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3057144 | 0.84 | SHBG (0.58) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL11508378 | 0.84 | SHBG (0.58) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL14713210 | 0.84 | SHBG (0.58) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL3073418 | 0.84 | SHBG (0.55) | SHBGALDH1A1NR3C1PGRADRA1A | |
| Potassium Ion SCHEMBL10786275 | 0.84 | SHBG (0.55) | SHBGALDH1A1NR3C1PGRADRA1A | |
| SCHEMBL10783952 | 0.83 | LMNA (0.55) | SHBGALDH1A1NR3C1PGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863760-B1 | USE OF ANTIMINERALOCORTICOID COMPOUNDS AGAINST DRUG WITHDRAWAL SYNDROME | AVENTIS PHARMA SA (FR) | 2001-12-05 | — | — | EP | claimed |